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Fmoc-NH-PEG11-CH2CH2COOH

Catalog No.GC60168

Fmoc-NH-PEG11-CH2CH2COOH es un enlazador PROTAC basado en PEG que se puede utilizar en la sÍntesis de PROTAC.

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Fmoc-NH-PEG11-CH2CH2COOH Chemical Structure

Tamaño Precio Disponibilidad Cantidad
100mg
343,00 $
Disponible
250mg
630,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Fmoc-NH-PEG11-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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