Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH₂ |
| Catalog No.GA20473 |
The potent anticoagulant E-76, Acetyl-ALCDDPRVDRWYCQFVEG-amide, is an inhibitor of coagulation factor VIIa. It has been suggested that E-76 works by binding to an exosite on the factor VIIa protease domain, and non-competitively inhibits activation of factor X and amidolytic activity. E-76 has a well defined structure in solution determined by NMR spectroscopy that is similar to the X-ray crystal structure when complexed with factor VIIa and represents a new framework for the development of inhibitors for serine proteases.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1926163-13-4
Sample solution is provided at 25 µL, 10mM.
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The potent anticoagulant E-76, Acetyl-ALCDDPRVDRWYCQFVEG-amide, is an inhibitor of coagulation factor VIIa. It has been suggested that E-76 works by binding to an exosite on the factor VIIa protease domain, and non-competitively inhibits activation of
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