Defensin 5 (human) |
Catalog No.GA21372 |
Human defensin-5 (HD 5) is a key regulator of gut microbiota homeostasis. HD 5 exhibits microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine. Reduction or absence of HD 5 release in the intestinal mucosa has been associated with susceptibility to enteric pathogens, changes in composition of the microbiota, and disruption of intestinal immune homeostasis. As a biomarker, HD 5 might be used to distinguish between ulcerative colitis (low levels of HD 5) or Crohn's colitis (high levels of HD 5).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Human defensin-5 (HD 5) is a key regulator of gut microbiota homeostasis. HD 5 exhibits microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine.Reduction or absence of HD 5 release in the intest
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