Fmoc-Pro-DHPP resin (200-400 mesh, 0.4-0.7 mmol/g) |
| Catalog No.GA21783 |
DHPP-resin, i.e. 4-(1',1'-dimethyl-1'-hydroxypropyl)phenoxyacetyl-alanyl-aminomethyl resin, has been developed especially for the synthesis of peptides containing a C-terminal proline. The bulkiness of the linker prevents diketopiperazine formation. As the esterification of Fmoc-Pro-OH (yielding a modified t-butyl ester) is impeded as well, the resin is offered as loaded derivative. Peptides can be cleaved from this resin applying the standard protocols for the cleavage from Wang resin. Fmoc-Pro-DHPP-resin is an alternative to H-Pro-ClTrt-resin (D-2000) not only if an increased acid stability is required. The resin is more polar than 2-chlorotrityl resin and the Pro residue is more accessible.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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DHPP-resin, i.e. 4-(1',1'-dimethyl-1'-hydroxypropyl)phenoxyacetyl-alanyl-aminomethyl resin, has been developed especially for the synthesis of peptides containing a C-terminal proline. The bulkiness of the linker prevents diketopiperazine formation. As
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GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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