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Fmoc-Ser(BSi)-OH

Catalog No.GA21793 Copy One-Click Copy Product Info

The BSi (or TBDMS) ether is somewhat more labile towards TFA than the tBu ether protection of the Ser hydroxyl moiety. Ser(TBDMS) can be cleaaved selectiviely in the presence of Boc/tBu with Bu?N fluoride in DMF, but Fmoc is removed under these conditions as well.

Products are for research use only. Not for human use. We do not sell to patients.

Fmoc-Ser(BSi)-OH Chemical Structure

Cas No.: 146346-81-8

Tamaño Precio Disponibilidad Cantidad
5g
29,00 $
Disponible
10g
53,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of Fmoc-Ser(BSi)-OH

The BSi (or TBDMS) ether is somewhat more labile towards TFA than the tBu ether protection of the Ser hydroxyl moiety. Ser(TBDMS) can be cleaaved selectiviely in the presence of Boc/tBu with BuN fluoride in DMF, but Fmoc is removed under these conditio

Chemical Properties of Fmoc-Ser(BSi)-OH

Cas No. 146346-81-8 SDF
Formula C24H31NO5Si M.Wt 441.6
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Fmoc-Ser(BSi)-OH

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.2645 mL 11.3225 mL 22.6449 mL
5 mM 452.9 μL 2.2645 mL 4.529 mL
10 mM 226.4 μL 1.1322 mL 2.2645 mL
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In vivo Formulation Calculator (Clear solution) of Fmoc-Ser(BSi)-OH

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Fmoc-Ser(BSi)-OH

Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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