Cyclic MKEY TFA |
Catalog No.GC35778 |
Cyclic MKEY TFA es un inhibidor peptÍdico cÍclico sintético de la formaciÓn de heterodÍmeros CXCL4-CCL5, que protege contra la aterosclerosis y la formaciÓn de aneurismas aÓrticos mediando la inflamaciÓn.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Cyclic MKEY TFA is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY TFA also protects against stroke-induced brain injury in mice[1][2]. CXCL4-CCL5[1]
[1]. Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615. [2]. Iida Y, et al. Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):718-26.
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