β-Amyloid (1-42), rat (Synonyms: Amyloid β-peptide (1-42) (rat/mouse)) |
Catalog No.GC37984 |
β-amiloide (1-42), la rata es un péptido de 42 aa, muestra un efecto citotÓxico en cortes agudos del hipocampo y se utiliza en la investigaciÓn de la enfermedad de Alzheimer's.
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Cas No.: 166090-74-0
Sample solution is provided at 25 µL, 10mM.
β-Amyloid (1-42), rat is a 42-aa peptide, shows cytotoxic effect on acute hippocampal slices, and used in the research of Alzheimer's disease. Amyloid-β[1]
β-Amyloid (1-42), rat shows cytotoxic effect on the hippocampal slices at 20 μM[1]. β-Amyloid (1-42), rat causes morphological changes in NGF-induced PC12 cells, induces formed cell processes to retract in differentiated cells and affect the expression of exons 2/3 in both undifferentiated and differentiated cells[2].
[1]. Mozes E, et al. A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays. Brain Res Bull. 2012 Apr 10;87(6):521-5. [2]. Lagunes T, et al. Abeta(1-42) induces abnormal alternative splicing of tau exons 2/3 in NGF-induced PC12 cells. An Acad Bras Cienc. 2014 Dec;86(4):1927-34.
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