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L-Methionine sulfoxide

Catalog No.GC38320 Copy One-Click Copy Product Info

El sulfÓxido de L-metionina (H-Met(O)-OH), un metabolito de la metionina, induce la polarizaciÓn de macrÓfagos clÁsicos/M1 y modula el estrés oxidativo y los parÁmetros de seÑalizaciÓn purinérgica.

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L-Methionine sulfoxide Chemical Structure

Cas No.: 3226-65-1

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL Water)
19,00 $
Disponible
500mg
18,00 $
Disponible
1g
28,00 $
Disponible
5g
69,00 $
Disponible
10g
105,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of L-Methionine sulfoxide

L-Methionine sulfoxide (H-Met(O)-OH), a metabolite of Methionine, induces M1/classical macrophage polarization, and modulates oxidative stress and purinergic signaling parameters[1].

[1]. Dos Santos LM, et al. Methionine and methionine sulfoxide treatment induces M1/classical macrophage polarization and modulates oxidative stress and purinergic signaling parameters. Mol Cell Biochem. 2017 Jan;424(1-2):69-78.

Chemical Properties of L-Methionine sulfoxide

Cas No. 3226-65-1 SDF
Canonical SMILES O=C(O)[C@@H](N)CCS(C)=O
Formula C5H11NO3S M.Wt 165.21
Solubility H2O : 100 mg/mL (605.29 mM; Need ultrasonic); DMSO : < 1 mg/mL (insoluble or slightly soluble) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of L-Methionine sulfoxide

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 6.0529 mL 30.2645 mL 60.529 mL
5 mM 1.2106 mL 6.0529 mL 12.1058 mL
10 mM 605.3 μL 3.0265 mL 6.0529 mL
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In vivo Formulation Calculator (Clear solution) of L-Methionine sulfoxide

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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