Karanjin |
| Catalog No.GC63934 |
Karanjin es un importante furanoflavonol activo constituyente de Fordia cauliflora. Karanjin induce la translocaciÓn de GLUT4 en las células del mÚsculo esquelético al aumentar la actividad de AMPK. Karanjin puede inducir la muerte de células cancerosas a través de la detenciÓn del ciclo celular y mejorar la apoptosis.
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Cas No.: 521-88-0
Sample solution is provided at 25 µL, 10mM.
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Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].
[1]. Jaiswal N, et al.Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. Eur J Pharmacol. 2011 Nov 16;670(1):22-8.
[2]. Guo JR, et al. Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancercells. Biol Res. 2015 Jul 26;48:40.
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