L-319 (Synonyms: Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) |
| Catalog No.GC49721 |
L-319 es un lipidoide catiónico ionizable y puede usarse para liposomas sintéticos, de la patente WO-2011153493-A2, compuesto 1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1351586-50-9
Sample solution is provided at 25 µL, 10mM.
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L-319 is an ionizable (pKa = 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.1 Administration of mouse factor VII-targeting siRNA in L-319-containing lipid nanoparticles induces factor VII silencing in mice.
1.Maier, M.A., M., J., Matsuda, S., et al.Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeuticsMol. Ther.21(8)1570-1578(2013)
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