MCHr1 antagonist 1 |
| Catalog No.GC31628 |
El antagonista 1 de MCHR1 es un antagonista selectivo del receptor de la hormona concentradora de melanina 1 (MCH1), con una Kb de 1 nM y una Ki de 4 nM en MCH1 humana, y puede usarse para reducir la masa corporal.
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Cas No.: 391610-37-0
Sample solution is provided at 25 µL, 10mM.
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MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].
[1]. Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1
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