MP07-66 |
| Catalog No.GC64031 |
MP07-66, un anÁlogo de FTY720, carece de efectos inmunosupresores y muestra efectos antitumorales prometedores en la leucemia linfocÍtica crÓnica mediante la interrupciÓn del complejo SET-PP2A que conduce a la reactivaciÓn de PP2A.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1938056-90-6
Sample solution is provided at 25 µL, 10mM.
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MP07-66, a FTY720 analogue, is devoid of immunosuppressive effects and shows promising antitumor effects in chronic lymphocytic leukemia by disruption of the SET-PP2A complex leading to PP2A reactivation[1].
[1]. Zonta F, et al. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. Blood. 2015;125(24):3747-3755.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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