MS1943 |
| Catalog No.GC39407 |
MS1943 es un degradador selectivo EZH2 biodisponible por vÍa oral, primero en su clase, con un IC50 de 120 nM. MS1943 reduce significativamente los niveles de proteÍna EZH2 en numerosos cÁnceres de mama triple negativos (TNBC) y otras lÍneas celulares cancerosas y no cancerosas. MS1943 bloquea eficazmente la proliferaciÓn de mÚltiples TNBC y otras lÍneas celulares de cÁncer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2225938-17-8
Sample solution is provided at 25 µL, 10mM.
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MS1943 is a first-in-class, orally bioavailable EZH2 selective degrader, with an IC50 of 120 nM. MS1943 significantly reduces EZH2 protein levels in numerous triple-negative breast cancer (TNBC) and other cancer and noncancerous cell lines. MS1943 effectively blocks proliferation of multiple TNBC and other cancer cell lines[1].
[1]. Ma A, et al. Discovery of a first-in-class EZH2 selective degrader.Nat Chem Biol. 2020 Feb;16(2):214-222.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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