PD 90780 (hydrate) |
| Catalog No.GC46197 |
An inhibitor of NGF-p75 NGFR interactions
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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PD 90780 is an inhibitor of the interaction between NGF and the p75 NGF receptor (NGFR).1 It binds to NGF (KD = 25.83 μM) and inhibits NGF binding to the extracellular domain of p75 NGFR (IC50 = 220 nM), as well as to Q1-CHO cells expressing full-length human p75 NGFR (IC50 = 300 nM).1,2 PD 90780 inhibits NGF-dependent differentiation of PC12 cells (IC50 = 33.22 μM).2
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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