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PF-06952229

Catalog No.GC39636

PF-06952229 es un inhibidor de TGFbR1 potente, selectivo y oralmente activo. PF-06952229 se une especÍficamente a TGFbR1 y evita la transducciÓn de seÑales mediada por TGFbR1. PF-06952229 es un agente antineoplÁsico prometedor para el estudio de tumores sÓlidos, especÍficamente cÁncer de mama metastÁsico.

Products are for research use only. Not for human use. We do not sell to patients.

PF-06952229 Chemical Structure

Cas No.: 1801333-55-0

Tamaño Precio Disponibilidad Cantidad
5mg
315,00 $
Disponible
10mg
540,00 $
Disponible
50mg
1.575,00 $
Disponible
100mg
2.520,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction. PF-06952229 is a promising antineoplastic agent for the study solid tumors, especifically metastatic breast cancer[1].

[1]. Flavia Mercer Pernasetti, et al. Combinations of tgfb inhibitors and cdk inhibitors for the treatment of breast cancer. Patent WO2020058820A1.

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Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

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