Skyrin (Synonyms: Endothianin, Rhodophyscin) |
| Catalog No.GC18532 |
Skyrin is a fungal metabolite characterized by a bisanthraquinone structure.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 602-06-2
Sample solution is provided at 25 µL, 10mM.
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Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 μM, skyrin reduces both glucagon-stimulated cAMP production and glycogenolysis. It does not interfere with epinephrine or glucagon-like peptide 1 effects on these parameters.[1]
Reference:
[1]. Parker, J.C., McPherson, R.K., Andrews, K.M., et al. Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes. Diabetes 49, 2079-2086 (2012).
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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