TH1834 dihydrochloride |
Catalog No.GC39303 |
El diclorhidrato de TH1834 es un inhibidor especÍfico de la histona acetiltransferasa Tip60 (KAT5). El diclorhidrato de TH1834 induce la apoptosis y aumenta el daÑo del ADN en el cÁncer de mama. El diclorhidrato de TH1834 no afecta la actividad de la histona acetiltransferasa MOF relacionada. Actividad anticancerÍgena.
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Cas No.: 2108830-09-5
Sample solution is provided at 25 µL, 10mM.
TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor. TH1834 dihydrochloride induces apoptosis and increases DNA damage in breast cancer. TH1834 dihydrochloride does not affect the activity of related histone acetyltransferase MOF. Anticancer activity[1].
[1]. Gao C, et al. Rational design and validation of a Tip60 histone acetyltransferase inhibitor. Sci Rep. 2014 Jun 20;4:5372.
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