Tivanisiran (Synonyms: SYL1001) |
| Catalog No.GC64852 |
Tivanisiran (SYL1001) es un siRNA utilizado para el estudio de la enfermedad del ojo seco.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1848224-71-4
Sample solution is provided at 25 µL, 10mM.
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Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1)[1].
In vitro transfection of tivanisiran was shown to produce a 50-60% decrease in TRPV1 mRNA levels[1][2].
[1]. Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to
[2]. Javier Moreno-MontaÑÉs, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.
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