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Tyk2-IN-9

Catalog No.GC39644

Tyk2-IN-9 (Compuesto 26) es un inhibidor selectivo de Tyk-2 con IC50 de 0,076 y 1,8 nM para TYK2-JH2 y JAK1-JH2, respectivamente.

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Tyk2-IN-9 Chemical Structure

Cas No.: 2127109-85-5

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5mg
510,00 $
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10mg
918,00 $
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50mg
2.364,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Tyk2-IN-9 is a potent,selective and specific inhibitor of JAK kinases, inhibits Tyk2, JAK1 and JAK2 with IC50 values of 6 nM, 21nM and 6nM, respectively. Tyk2-IN-9, example 19, is extracted from patent US2017240552A1[1].

[1]. Matthew Frank Brown, et al. Pyrazolo[1,5-a]pyrazin-4-yl derivatives. Patent US20170240552A1

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