UAA crosslinker 1 |
Catalog No.GC32461 |
El clorhidrato del reticulador 1 de UAA es un codÓn Ámbar que se utiliza para la incorporaciÓn de aminoÁcidos no canÓnicos (ncAA). Los ncAA se pueden incorporar en proteÍnas in vivo haciendo uso de la actividad promiscua de ciertas aminoacil-tRNA sintetasas de tipo salvaje y modificadas genéticamente.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1167421-25-1
Sample solution is provided at 25 µL, 10mM.
UAA crosslinker 1 act as substrates for pylRS/tRNA pair that enable its incorporation into a target protein.
[1]. VanBrunt MP, et al. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry. Bioconjug Chem. 2015 Nov 18;26(11):2249-60.
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