2,2,2-Trichloroethanol |
| رقم الكتالوجGC60455 |
2،2،2-Trichloroethanol ، الشكل النشط لهيدرات الكلورال ، هو ناهض لقنوات K2P غير الكلاسيكية TREK-1 (KCNK2) و TRAAK (KCNK4)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 115-20-8
Sample solution is provided at 25 µL, 10mM.
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2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1].
2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery[1].
[1]. Nikhil K Parelkar , et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10.
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