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2,2,2-Trichloroethanol

Catalog No.GC60455

El 2,2,2-tricloroetanol, la forma activa del hidrato de cloral, es un agonista de los canales K2P no clÁsicos TREK-1 (KCNK2) y TRAAK (KCNK4).

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2,2,2-Trichloroethanol Chemical Structure

Cas No.: 115-20-8

Tamaño Precio Disponibilidad Cantidad
500mg
46,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1].

2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery[1].

[1]. Nikhil K Parelkar , et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10.

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