الصفحة الرئيسية>>Plant Biology>>2,3-Oxidosqualene

2,3-Oxidosqualene (Synonyms: (3R,S)-Oxidosqualene, Squalene 2,3-oxide)

رقم الكتالوجGC49671

An intermediate in the biosynthesis of sterols

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2,3-Oxidosqualene التركيب الكيميائي

Cas No.: 7200-26-2

الحجم السعر المخزون الكميّة
1 mg
190٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of 2,3-Oxidosqualene

2,3-Oxidosqualene is an intermediate in the biosynthesis of sterols such as lanosterol , cycloartenol, and cholesterol .1,2 It is also an intermediate in the biosynthesis of the triterpenoid β-amyrin .3

1.Nes, W.D.Biosynthesis of cholesterol and other sterolsChem. Rev.111(10)6423-6451(2011) 2.Willett, J.D., Sharpless, K.B., Lord, K.E., et al.Squalene-2,3-oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterolJ. Biol. Chem.242(18)4182-4191(1967) 3.Kajikawa, M., Yamato, K.T., Fukuzawa, H., et al.Cloning and characterization of a cDNA encoding beta-amyrin synthase from petroleum plant Euphorbia tirucalli LPhytochemistry66(15)1759-1766(2005)

Chemical Properties of 2,3-Oxidosqualene

Cas No. 7200-26-2 SDF
المرادفات (3R,S)-Oxidosqualene, Squalene 2,3-oxide
Canonical SMILES C/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C=C(C)/CC/C=C(C)/CCC1C(C)(O1)C
Formula C30H50O M.Wt 426.7
الذوبان Chloroform: slightly Storage -80°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 2,3-Oxidosqualene

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.3436 mL 11.7178 mL 23.4357 mL
5 mM 0.4687 mL 2.3436 mL 4.6871 mL
10 mM 0.2344 mL 1.1718 mL 2.3436 mL
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In vivo Formulation Calculator (Clear solution) of 2,3-Oxidosqualene

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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