الصفحة الرئيسية>>Signaling Pathways>> Membrane Transporter/Ion Channel>> CRAC Channel>>5J 4

5J 4

رقم الكتالوجGC50179

5J 4 هو مثبط قوي لـ CRAC.

Products are for research use only. Not for human use. We do not sell to patients.

5J 4 التركيب الكيميائي

Cas No.: 827001-82-1

الحجم السعر المخزون الكميّة
10 mg
167٫00
متوفر
50 mg
702٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Calcium release-activated calcium (CRAC) channel blocker. Blocks store-operated calcium entry (SOCE) in HeLa-O+S cells and Th17 cells in vitro. Ameliorates symptoms and reduces CNS infiltration by mononuclear cells in a mouse model of experimental autoimmune encephalomyelitis (EAE) in vivo.

Kim et al (2014) Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation. J.Immunol. 192 110 PMID:24307733

مراجعات

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