Aurora Kinase Inhibitor II (Synonyms: 4-(4-Benzamidoanilino)-6,7-dimethoxyquinazoline) |
| رقم الكتالوجGC40667 |
Aurora Kinase Inhibitor II هو مثبط Aurora kinase انتقائي وتنافسي ATP مع IC50s من 310 نانومتر و 240 نانومتر لـ Aurora A و Aurora B ، على التوالي.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 331770-21-9
Sample solution is provided at 25 µL, 10mM.
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The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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