>>Signaling Pathways>> Chromatin/Epigenetics>> Aurora Kinase>>Aurora Kinase Inhibitor II

Aurora Kinase Inhibitor II (Synonyms: 4-(4-Benzamidoanilino)-6,7-dimethoxyquinazoline)

Catalog No.GC40667

Aurora Kinase Inhibitor II는 Aurora A 및 Aurora B에 대해 IC50이 각각 310nM 및 240nM인 선택적 및 ATP-경쟁적 Aurora 키나제 억제제입니다.

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Aurora Kinase Inhibitor II Chemical Structure

Cas No.: 331770-21-9

Size 가격 재고 수량
5 mg
US$357.00
재고 있음
10 mg
US$591.00
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25 mg
US$1,122.00
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50 mg
US$1,733.00
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100 mg
US$2,549.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.

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