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Avitinib (Synonyms: AC0010)

رقم الكتالوجGC42884

Avitinib (AC0010) هو مثبط EGFR انتقائي لا رجعة فيه ، يمنع بشكل فعال طفرات مقاومة EGFR T790M في سرطان الرئة ذو الخلايا غير الصغيرة (NSCLC)Abivertinib هو أيضًا مثبط جديد لـ BTK

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Avitinib التركيب الكيميائي

Cas No.: 1557267-42-1

الحجم السعر المخزون الكميّة
1mg
49٫00
متوفر
5mg
63٫00
متوفر
10mg
111٫00
متوفر
25mg
204٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

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    GlpBio Citations
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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR). It is selective for EGFR-active and T790M mutations, exhibiting a 298-fold increase in potency compared with wild-type EGFR. In a xenograft model, oral administration of 500 mg/kg avitinib was shown to result in complete remission of tumors with EGFR-active and T790M mutations.

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 23 reference(s) in Google Scholar.)

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