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Avitinib (Synonyms: AC0010)

Catalog No.GC42884

Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR).

Products are for research use only. Not for human use. We do not sell to patients.

Avitinib Chemical Structure

Cas No.: 1557267-42-1

Size Price Stock Qty
1mg
$49.00
In stock
5mg
$63.00
In stock
10mg
$111.00
In stock
25mg
$204.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR). It is selective for EGFR-active and T790M mutations, exhibiting a 298-fold increase in potency compared with wild-type EGFR. In a xenograft model, oral administration of 500 mg/kg avitinib was shown to result in complete remission of tumors with EGFR-active and T790M mutations.

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Average Rating: 5 ★★★★★ (Based on Reviews and 23 reference(s) in Google Scholar.)

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