Avitinib (Synonyms: AC0010) |
Catalog No.GC42884 |
Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1557267-42-1
Sample solution is provided at 25 µL, 10mM.
Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR). It is selective for EGFR-active and T790M mutations, exhibiting a 298-fold increase in potency compared with wild-type EGFR. In a xenograft model, oral administration of 500 mg/kg avitinib was shown to result in complete remission of tumors with EGFR-active and T790M mutations.
Average Rating: 5
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