BAY-1797 |
| رقم الكتالوجGC39344 |
BAY-1797 هو مضاد P2X4 فعال وفعال عن طريق الفم وانتقائي ، مع IC50 من 211 نانومتر ضد الإنسان P2X4
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2055602-83-8
Sample solution is provided at 25 µL, 10mM.
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BAY-1797 is a potent, orally active, and selective P2X4 antagonist, with an IC50 of 211 nM against human P2X4. BAY-1797 displays no or very weak activity on the other P2X ion channels. BAY-1797 shows anti-nociceptive and anti-inflammatory effects[1].
[1]. Werner S, et al. Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile. J Med Chem. 2019 Dec 26;62(24):11194-11217.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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