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Beraprost sodium

رقم الكتالوجGC38891

Beraprost sodium ، نظير البروستاسكلين ، هو دواء أولي مستقر وفعال عن طريق الفم لـ PGI2

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Beraprost sodium التركيب الكيميائي

Cas No.: 496807-11-5

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
297٫00
متوفر
5mg
270٫00
متوفر
10mg
450٫00
متوفر
25mg
855٫00
متوفر
50mg Please Inquire Please Inquire
100mg Please Inquire Please Inquire

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Beraprost sodium, a prostacyclin analog, is a stable and orally active prodrug of PGI2. Beraprost sodium is a potent vasodilator, has the potential for pulmonary arterial hypertension treatment through expanding renal vessels, improving microcirculation[1].

Beraprost sodium (0.1, 1.0, and 10.0 μM; 24 hours) treatment leads to a significant increase in the number of tube formation, BPS plays an important role on angiogenic activity[1]. Beraprost sodium (0.1, 1.0, and 10.0 μM; 24 hours) treatment let VE-cadherin at regions of cell-cell contact becomes more abundant and the morphology of endothelial cells tends to be normal compared with those cultured under hypoxia conditions[1].

Beraprost sodium (oral adminstration; 0.6 mg/kg; once daily; 3 or 7 days) can mitigate the development of renal interstitial fibrosis, decrease renal oxidative stress through its potential vasodilation effect, and further prevent renal interstitial fibrosis[1]. Animal Model: 6-8-week-old C57Bl/6J Male Mice[1]

[1]. Li S, et al. Beraprost sodium mitigates renal interstitial fibrosis through repairing renal microvessels.J Mol Med (Berl). 2019 Jun;97(6):777-791.

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