1-Deoxynojirimycin (DNJ) chemical formula C6H13NO4 and molecular weight of 163.17 g/mol, is a type of indigenous alkaloid examined in mulberry leaves, insects, and the culture broth of some microbes as a product of secondary metabolites such as Commelina communis, and bacterial strains including Bacillus and Streptomyces species. As a representative iminopyranose, 1-Deoxynojirimycin exhibits α-glucosidase inhibitor activity along with anti-viral, anti-diabetic, anti-inflammatory, anti-obesity, and antioxidant properties employed for several applications.

Pembrolizumab, marketed under the brand name Keytruda, is a monoclonal antibody used in cancer immunotherapy. It targets the programmed cell death protein 1 (PD-1) receptor on T cells, a critical checkpoint in the immune system.

SBFI-26 is a fatty acid binding protein inhibitor and it binds to anandamide transporters FABP5 and FABP7 at two different sites.

With respect to longevity and enhanced health, scientists have turned their attention towards a remarkable molecule: Beta Nicotinamide Mononucleotide (NMN). It’s a derivative of Vitamin B3 (niacin), has gained attention for its potential to modulate cellular function, combat the aging, and promote overall well-being. β-Nicotinamide mononucleotide (NMN) is a natural product which exists in small quantity in most plants, such as edamame, broccoli, and cucumber.

Atezolizumab is an Fc-engineered , humanized, monoclonal antibody that targets programmed death ligand 1 (PD-L1). Atezolizumab prevents the binding of PD-L1 to receptors programmed death 1 (PD-1) and B7.

By searching deep in the field of cellular biology by using the microscopic aspects, we revealed the surprising molecule under the name of 3-Methyladenine (3-MA), a compound that does not have its recognization under the heading of DNA or proteins, but play a vital role in the front line of cellular processes.

In the ever-evolving landscape of biomedical research, a new star is rising, capturing the attention of scientists and researchers worldwide. This star is none other than Tat-NR2B9c, a peptide whose unique properties and potential applications are setting the stage for groundbreaking advancements in medicine and therapeutic treatment.

TAK-242 ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate, also known as resatorvid, is a cyclohexene derivative and a small inhibitor molecule of TLR4 signaling, which was first represented as a novel anti-sepsis treatment that may inhibit the production of inflammatory mediators. Research on the mechanisms of action has revealed that TAK-242 specifically binds to Cys747 in the TIR domain of TLR4, which ensuingly prevents TLR4 from interacting with TIRAP.

Pseudomonas aeruginosa produces copious amounts of the redox-active tricyclic phenazine compound pyocyanin ( chloroform-soluble) that kills competing microbes and mammalian cells, especially during cystic fibrosis ,lung infection. Pyocyanin is responsible for the blue-green colour chacteristics of pseudomonas species. The pigment pyocyanin is composed of 2 subunits of N-methyl-1-hydroxyphenazine .

In the annals of medical research, serendipity often plays a pivotal role in leading scientists down unforeseen paths that dramatically alter our understanding of human health and disease. Such is the role of MPTP (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) hydrochloride, a compound whose story intertwined with the fates of a few, yet has illuminated the path for many in the battle against Parkinson’s disease. This blog article embarks on a journey through the discovery of MPTP hydrochloride, its profound impacts on neuroscience, and the ongoing quest to conquer neurodegenerative disorders.