Epibetulinic acid |
| رقم الكتالوجGC60152 |
يُظهر حمض Epibetulinic تأثيرات مثبطة قوية على إنتاج NO و prostaglandin E2 (PGE2) في الضامة الفأرية (RAW 264.7) محفزًا بالسموم الداخلية البكتيرية مع IC50s 0.7 و 0.6 ميكرومتر ، على التوالي
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Cas No.: 38736-77-5
Sample solution is provided at 25 µL, 10mM.
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Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.
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