Epibetulinic acid |
| Catalog No.GC60152 |
에피베툴린산은 IC50이 각각 0.7 및 0.6 μM인 박테리아 내독소로 자극된 마우스 대식세포(RAW 264.7)에서 NO 및 프로스타글란딘 E2(PGE2) 생성에 대한 강력한 억제 효과를 나타냅니다.
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Cas No.: 38736-77-5
Sample solution is provided at 25 µL, 10mM.
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Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.
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