Desethyl Hydroxychloroquine-d4 (Synonyms: Cletoquine-d4, (±)-Desethylhydroxychloroquine-d4, DHCQ-d4) |
| رقم الكتالوجGC47193 |
An internal standard for the quantification of desethyl hydroxychloroquine
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1854126-47-8
Sample solution is provided at 25 µL, 10mM.
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Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1 It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)
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