Autoimmunity
منتجات لـ نبسب؛ Autoimmunity
- القط. رقم اسم المنتج بيانات
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GC52253
α-Enolase (1-19)-biotin Peptide
Enolase-1 (1-19)-biotin
A biotinylated α-enolase peptide -
GC48292
α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
α-Melanocyte-stimulating Hormone, Ac-SYSMEHFRWGKPV-NH2
α ؛ -MSH (α ؛ -هرمون تحفيز الخلايا الصغرى) TFA ، وهو ببتيد عصبي داخلي ، وهو ناهض لمستقبل الميلانوكورتين 4 (MC4R) مع أنشطة مضادة للالتهابات وخافض للحرارة. -
GC40467
(±)11-HETE
(±)11-Hydroxyeicosatetraenoic Acid
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. -
GC45263
(+)-D-threo-PDMP (hydrochloride)
D-PDMP
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. -
GC52185
(R,S)-Anatabine-d4
(±)-Anatabine-d4
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GC18773
(Rac)-Benpyrine
(Rac) -Benpyrine ، زميل سباق من Benpyrine ، هو مثبط قوي وفعال عن طريق الفم لـ TNF-α.
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GC90774
1-Linoleoyl Lysophosphatidic Acid (sodium salt)
جليسيرفوسفوليبيد
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GC46499
1-Stearoyl-rac-glycerol-d40
18:0-d40-MG, 1-Monostearin-d40, MG(18:0-d40/0:0/0:0)
A neuropeptide with diverse biological activities -
GC49759
13C17-Mycophenolic Acid
13C17-MPA
An internal standard for the quantification of mycophenolic acid -
GC49912
13C20,15N10-Cyclic di-GMP (sodium salt)
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid
An internal standard for the quantification of cyclic di-GMP -
GC41950
16α-hydroxy Estrone
16α-hydroxy E1, 16αOHE1
16α ؛ -هيدروكسي إسترون (16α ؛ OHE) هو مستقلب استراديول رئيسي. -
GC42080
2'2'-cGAMP (sodium salt)
Adenosine-Guanosine 2’,2’-cyclic monophosphate, cGAMP(2’-5’), 2’,2’-Cyclic GMP-AMP
2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. -
GC40960
20α-dihydro Prednisolone
20α-DHP, 20α-dihydro-PRED, 20(R)-hydroxy Prednisolone, 20α-hydroxy Prednisolone
20α-dihydro Prednisolone is a metabolite of prednisolone. -
GC18527
4'-hydroxy Flurbiprofen
A major active metabolite of flurbiprofen
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GC49127
4-oxo Cyclophosphamide
4-keto CP, 4-keto Cyclophosphamide, NSC 139488, 4-oxo CP
An inactive metabolite of cyclophosphamide -
GC18582
5'-hydroxy Meloxicam
A metabolite of meloxicam
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GC48381
5'-pApA (sodium salt)
c-di-AMP Control, Cyclic di-AMP Negative Control
A linearized form of cyclic di-AMP -
GC48375
5'-pGpG (sodium salt)
c-di-GMP Control, Cyclic di-GMP Negative Control
A linearized form of cyclic di-GMP -
GC52413
5-Aminosalicylic Acid-d7
5-ASA-d7, Mesalamine-d7, Mesalazine-d7
An internal standard for the quantification of 5-aminosalicylic acid -
GC49629
6β-hydroxy Prednisolone
A metabolite of prednisolone
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GC45772
6(5H)-Phenanthridinone
NSC 11021, NSC 40943, NSC 61083
An inhibitor of PARP1 and 2 -
GC49235
6-Methylmercaptopurine
6-MMP, 6-(Methylthio)purine, NSC 20105, SQ 8,343
A metabolite of 6-mercaptopurine -
GC49488
6-Methylmercaptopurine-d3
6-MMP-d3, 6-(Methylthio)purine-d3
An internal standard for the quantification of 6-MMP -
GC49051
7-hydroxy Methotrexate
NSC 380962, 7-hydroxy MTX
7-هيدروكسي الميثوتريكسات هو مستقلب رئيسي للميثوتريكسات -
GC42608
7-hydroxy Methotrexate (sodium salt)
7-hydroxy MTX
7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.
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GC42644
9-Deazaguanine
NSC 344522
9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). -
GC49238
93-O17S
A cationic lipidoid
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GC42691
Aceclofenac ethyl ester
A potential impurity found in commercial preparations of aceclofenac
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GC42692
Aceclofenac methyl ester
Aceclofenac Impurity D
A potential impurity in commercial preparations of aceclofenac -
GC45762
Acitretin-d3
Ro 10-1670-d3
A neuropeptide with diverse biological activities -
GC40645
Actarit
4-Acetylaminophenylacetic Acid, MS-932, NSC 170317
أكتاريت ، مركب مضاد للروماتيزم فعال عن طريق الفم ، لديه القدرة على علاج التهاب المفاصل الناتج عن الكولاجين من النوع الثاني -
GC45375
ACTH (1-39) (trifluoroacetate salt)
Adrenocorticotropic Hormone (1-39)
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GC45681
AKP-11
An S1P1 receptor agonist
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GC26242
Alexa Fluor 594 labeled Concanavalin A
Concanavalin Afrom Canavalla ensiformis (Jack bean), Alexa Fluor 594 ConiugateAlexa Fluor 594-ConA:Alexa Fluor 594 labeled Concan avalin A (ConA): ConAlectin(Alexa Fluor 594):
Concanavalin ACon A, derived from Canavalia ensiformis beans, is a lectin protein (Mw 104 kDa).
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GC46867
Apremilast-d5
APR-d5
Apremilast D5 (CC-10004 D5) هو الديوتيريوم المسمى Apremilast -
GC45790
Artesunate-d4
Artesunic Acid-d4
الأرتيسونات- d4 هو الديوتيريوم المسمى Artesunateالأرتيسونات مثبط لكل من STAT-3 والبروتين المصدر 1 (EXP1) -
GC42856
AS-605240 (potassium salt)
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of PI at the three position to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3.
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GC46895
Aurintricarboxylic Acid (ammonium salt)
ATA
A protein synthesis inhibitor with diverse biological activities -
GC49646
Aurothioglucose (hydrate)
Gold Thioglucose
A TrxR inhibitor -
GC42877
AUY954
AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells).
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GC42880
Avenanthramide-C methyl ester
Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM).
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GC45820
Balsalazide-d4
Balsalazide-d4 هو الديوتيريوم المسمى بالسالازيد
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GC91659
BDW-OH
BDW-OH is an active metabolite of the STING agonist and prodrug BDW568 .
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GC91379
BDW568
BDW568 هو محفز لجينات المناعة الإنترفيرونية (STING) وهو شكل دواء مسبق لـ BDW-OH.
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GC49836
Benoxaprofen
LRCL 3794, NSC 299582
البينوكسابروفين (LRCL 3794) هو مركب قوي وطويل الأمد مضاد للالتهابات وخافض للحرارة -
GC91947
BH400
ويعمل BH400 كناهض للمستقبل α المنشط بناشر البيروكسيسوم ومثبط لمنبه جينات الإنترفيرون (STING ؛ الجرعة المميتة المتوسطة = 8.1 ميكرون).
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GC19069
BI605906
BI605906 is a novel IKKβ inhibitor with an IC50 value of 380 nM when assayed at 0.1 mM ATP.
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GC52326
Biotin-PEG4-LL-37 (human) (trifluoroacetate salt)
A biotinylated and pegylated form of LL-37
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GC42953
BMS 345541 (trifluoroacetate salt)
BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM).
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GC46946
BPC 157 (acetate)
GEPPPGKPADDAGLV, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
A pentadecapeptide with diverse biological activities -
GC90705
BSP-16
محفز STING
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GC46983
C-170
C-170 (C-170) هو مثبط قوي للالسعة التساهمية.
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GC46984
C-171
C-171 هو مثبط لمحفز جينات الإنترفيرون (STING).
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GC40570
C-178
C-178 is a covalent inhibitor of STING.
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GC43007
C12 Galactosylceramide (d18:1/12:0)
N-Dodecanoyl-β-D-Galactosylceramide, Galactosylceramide (d18:1/12:0), GalCer(d18:1/12:0)
C12 Galactosylceramide is a bioactive sphingolipid. -
GC46985
C18 3'-sulfo Galactosylceramide-d3 (d18:1/18:0-d3)
N-Octadecanoyl Sulfatide-d3, N-ω-CD3-Octadecanoyl-sulfatide
A neuropeptide with diverse biological activities -
GC43076
C24 Phytosphingosine (t18:0/24:0)
Ceramide (t18:0/24:0), Cer(t18:0/24:0), C24:0 Phytoceramide, N-Lignoceroyl Phytosphingosine, NTetracosanoyl Phytosphingosine
C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. -
GC43077
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
(3’-sulfo)Galβ-Cer(d18:1/24:1), N-Nervonoyl Sulfatide, C24:1 Sulfatide, cis-Tetracosenoyl Sulfatide, N-Tetracosenoyl (cis-15) Sulfatide
C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. -
GC47020
Calcium D-Glucarate (hydrate)
Calcium D-Saccharate, D-Glucaric Acid Calcium Salt, D-Saccharic Acid Calcium Salt
The calcium salt form of D-glucaric acid -
GC49147
Carboxyphosphamide
CPCOOH, NSC 145124
An inactive metabolite of cyclophosphamide -
GC43176
CAY10575
IKK2 Inhibitor 3, Polo-like Kinase Inhibitor 1
CAY10575 (المركب 8) هو مثبط IKK2 مع IC50 من 0.075 μ ؛ M. -
GC90710
CAY10723 (hydrochloride)
مثبط PAD2
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GC47054
CAY10748
A STING agonist
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GC45885
Chloroquine-d5 (phosphate)
DL-Chloroquine-d5
An internal standard for the quantification of chloroquine -
GC52351
Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide
Citrullinated Enolase-1-biotin, α-Enolase Peptide (Citrulline Residues 8 + 14)
A biotinylated and citrullinated α-enolase peptide -
GC52363
Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide
Biotin-A-Cit-TKQTA-Cit-KSTGGKAP-Cit-KQLA, Biotin-AXTKQTAXKSTGGKAPXKQLA (X=Citrulline), Citrullinated Histone H3.1-biotin
A biotinylated and citrullinated histone H3 peptide
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GC52367
Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide
Biotin-GQGKS(Cit)L(Cit)DLYEEEMRELRRQ, Biotin-GQGKSXLXDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (G146R) (R144 + R146)-biotin
A biotinylated and citrullinated mutant vimentin peptide -
GC52370
Citrullinated Vimentin (R144) (139-159)-biotin Peptide
Biotin-GQGKS(Cit)LGDLYEEEMRELRRQ, Biotin-GQGKSXLGDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (R144)-biotin
A biotinylated and citrullinated vimentin peptide -
GC49680
Clobetasone Propionate
Clobetasone 17-Propionate
A corticosteroid -
GC18572
Concanavalin A
ينتمي كونكانامايسين أ إلى الكونكانامايسينات، وهو عائلة من المضادات الحيوية الماكرولايد التي تم فصلها من ستربتومايس دِّستاتُخْرومجِـــــِــِذَالأزرق والتى تعد مثبطات نشطة للغاية وانتقائية لبروتون-ATPase (v-[H+] ATPase) في الفجاءة.
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GC45413
Cridanimod (sodium salt)
10-Carboxymethyl-9-Acridanone
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GC45614
Cryogenine
NSC 272693
An alkaloid with anti-inflammatory activity -
GC47128
CU-32
A cGAS inhibitor
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GC47129
CU-76
A cGAS inhibitor
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GC19526
Cyclic di-GMP disodium
c-di-GMP, Cyclic diguanylate, 3',5'-Cyclic diguanylic acid
Cyclic di-GMP (ملح الصوديوم) هو ناهض لاذع ورسول ثان للبكتيريا ينسق جوانب مختلفة من نمو البكتيريا وسلوكها ، بما في ذلك الحركة ، والفوعة ، وتكوين الأغشية الحيوية ، وتطور دورة الخلية. يحتوي Cyclic di-GMP (ملح الصوديوم) على نشاط مضاد لتكاثر الخلايا السرطانية ويحفز أيضًا تعبير مستقبل CD4 المرتفع وتوقف دورة الخلية. يمكن استخدام Cyclic di-GMP (ملح الصوديوم) في أبحاث السرطان. -
GC43340
Cyclic di-IMP (sodium salt)
c-di-IMP, Cyclic di-inosine monophosphate
Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP. -
GC48397
Cyclic di-UMP (sodium salt)
c-di-UMP, c-UpUp, Cyclic di-Uridine monophosphate, 3’3’-Cyclic UMP-UMP
A pyrimidine-containing CDN -
GC47148
Cyclophosphamide-d4
سيكلوفوسفاميد- d4 هو الديوتيريوم المسمى سيكلوفوسفاميدسيكلوفوسفاميد Cyclophosphamide هو عامل ألكلة اصطناعي مرتبط كيميائياً بخردل النيتروجين مع نشاط مضاد للأورام ، وهو مثبط للمناعة
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GC47193
Desethyl Hydroxychloroquine-d4
Cletoquine-d4, (±)-Desethylhydroxychloroquine-d4, DHCQ-d4
An internal standard for the quantification of desethyl hydroxychloroquine -
GC47198
Desoximetasone-d3
17-deoxy Dexamethasone-d3
A neuropeptide with diverse biological activities -
GC47202
Dexamethasone-d4
A neuropeptide with diverse biological activities
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GC43444
Diclofenac Acyl-β-D-Glucuronide
Diclofenac Glucuronide, Diclofenac-β-D-glucuronide
Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat. -
GC47212
Diclofenac amide
Diclofenac Lactam, 1-(2,6-Dichlorophenyl)oxindole, NSC 621845
A prodrug form of diclofenac -
GC43447
Diclofenac methyl ester
Methanol Diclofenac ester
Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. -
GC47213
Diclofenac-d4
An internal standard for the quantification of diclofenac
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GC40867
Diflorasone Diacetate
U-34865
ثنائي أسيتات ديفلوراسون هو مركب ستيرويد مضاد للالتهابات يستخدم كعامل محلي أو موضعي -
GC43494
DL-threo-PDMP (hydrochloride)
DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP.
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GC52334
ENPP1 Inhibitor 4e
cGAMP-compound 4e
An ENPP1 inhibitor -
GC52303
Ethyl Mycophenolate
A potential impurity found in commercial preparations of mycophenolate mofetil
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GC47321
Etifoxine-13C-d3
A neuropeptide with diverse biological activities
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GC47323
Etofenamate-d4
An internal standard for the quantification of etofenamate
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GC91921
Fenclofenac
RX-67408
يعتبر Fenclofenac دواء مضاد للالتهاب غير ستيرويدي (NSAID) ومثبط كوكس (IC50s = 7 و 4 ميكرو متر لكوكس -1 و كوكس -2 على التوالي). -
GC91909
Fenoprofen-13C6 (sodium salt hydrate)
تم تصميم Fenoprofen-13C6 (sodium salt hydrate) للاستخدام كمعيار داخلي لقياس الفينوبروفين بواسطة GC أو LC-MS.
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GC40565
Feprazone
Feprazone (DA2370 ؛ Prenazone) ، نظير من Phenylbutazone ، هو عامل مضاد للالتهابات مع أنشطة مسكنة وخافضة للحرارة.
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GC46148
Filgotinib-d4
GLPG0634-d4
Filgotinib-d4 (GLPG0634-d4) هو الديوتيريوم المسمى FilgotinibFilgotinib (GLPG0634) هو مثبط انتقائي JAK1 مع IC50 من 10 نانومتر و 28 نانومتر و 810 نانومتر و 116 نانومتر لـ JAK1 و JAK2 و JAK3 و TYK2 ، على التوالي -
GC47366
Flurbiprofen-d3
An internal standard for the quantification of flurbiprofen
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GC49074
Forphenicine
A bacterial metabolite and an inhibitor of alkaline phosphatase
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GC52487
Ganglioside GM4 (chicken egg) (ammonium salt)
Ganglioside G7, Monosialoganglioside GM4
A sphingolipid -
GC64257
Gelsevirine
Gelsevirine هو قلويد رئيسي في Gelsemium elegans مع تأثيرات مزيل القلق القوية
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GC20007
Ginsenoside CK
Ginsenoside Compound K, Ginsenoside IH901; Compound K
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.