WQ3810 (KPI-10 free base) (Synonyms: KPI-10 free base) |
| رقم الكتالوجGC32370 |
WQ3810 (قاعدة خالية من KPI-10) عبارة عن فلوروكينولون نشط عن طريق الفم ، مع أنشطة قوية مضادة للجراثيم.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 888032-58-4
Sample solution is provided at 25 µL, 10mM.
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WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.
WQ-3810 shows potent activity against A. baumannii, including MDR isolates, with MIC90 of 1 mg/L, more than eight-fold higher than that of ciprofloxacin (64 mg/L) and levofloxacin (8 mg/L). WQ-3810 also exhibits inhibitory effects on E. coli and S. pneumoniae, including FQR isolates, with MIC90 of 4 mg/L and 0.06 mg/L, respectively. WQ-3810 is the most potent among the fluoroquinolones tested against meticillin-resistant Staphylococcus aureus (MRSA) and Neisseria gonorrhoeae, including FQR isolates[1].
[1]. Kazamori D, et al. In vitro activity of WQ-3810, a novel fluoroquinolone, against multidrug-resistant and fluoroquinolone-resistant pathogens. Int J Antimicrob Agents. 2014 Nov;44(5):443-9.
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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