الصفحة الرئيسية>>CPTH6 (hydrobromide)

CPTH6 (hydrobromide)

رقم الكتالوجGC43321

CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP.

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CPTH6 (hydrobromide) التركيب الكيميائي

Cas No.: 2321332-57-2

الحجم السعر المخزون الكميّة
1mg
49٫00
متوفر
5mg
225٫00
متوفر
10mg
398٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

    GlpBio Citations
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP. It blocks the acetylation of H3/H4 histones and α-tubulin in several leukemia cell lines. CPTH6 reduces cell viability, arresting cell cycling in the G0/G1 phase and inducing apoptosis. It impairs autophagy in a variety of tumor cell lines, at least in part by altering ATG7-mediated elongation of autophagosomal membranes.

مراجعات

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