JTV-519 free base (Synonyms: K201 free base) |
| رقم الكتالوجGC36371 |
القاعدة الحرة JTV-519 (قاعدة خالية من K201) هي مانع معتمد على Ca2 +- لشبكة الهيولى العضلية Ca2 +- المحفز ATPase (SERCA) وناهض جزئي لمستقبلات الريانودين في العضلات المخططة
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Cas No.: 145903-06-6
Sample solution is provided at 25 µL, 10mM.
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JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].
[1]. Darcy YL, et al. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.
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