CAY10723 (Synonyms: AFM30a, AMF30a) |
| رقم الكتالوجGC43202 |
CAY10723 هو مثبط قوي لإنزيم بروتين أرجينين دايميناز 2 (PAD2) ولديه اختيارية ممتازة تجاه PAD2.
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Cas No.: 2095107-57-4
Sample solution is provided at 25 µL, 10mM.
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CAY10723 is an inhibitor of protein arginine deiminase 2 (PAD2) that binds to PAD2 in a target engagement assay (EC50 = 9.5 μM in HEK293/PAD2 cells). It is 1.6-, 47-, and ~15-fold selective for PAD2 over PAD1, PAD3, and PAD4, respectively. CAY10723 inhibits histone H3 citrullination in HEK293/PAD2 cells (EC50 = 0.4 μM).
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