الصفحة الرئيسية>>Signaling Pathways>> PROTAC>> Ligand for E3 Ligase>>E3 ligase Ligand 1 dihydrochloride

E3 ligase Ligand 1 dihydrochloride

رقم الكتالوجGC34291

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E3 ligase Ligand 1 dihydrochloride التركيب الكيميائي

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
253٫00
متوفر
100mg
230٫00
متوفر
500mg
689٫00
متوفر
1g
1103٫00
متوفر
2g
1655٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology.

E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology. E3 ligase Ligand 1 is a part of the active BRD4 PROTAC ARV-771, wich is a potent pan-BET degrader with antitumor activity[1].

[1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.

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