E3 ligase Ligand 1 dihydrochloride |
| Catalog No.GC34291 |
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology.
E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology. E3 ligase Ligand 1 is a part of the active BRD4 PROTAC ARV-771, wich is a potent pan-BET degrader with antitumor activity[1].
[1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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