Ethylmalonyl Coenzyme A (Synonyms: Ethylmalonyl-CoA) |
| رقم الكتالوجGC19430 |
A key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism
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Cas No.: 6049-57-6
Sample solution is provided at 25 µL, 10mM.
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Ethylmalonyl coenzyme A (CoA) is a key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism in certain bacteria, such as M. extorquens, which uses this pathway when grown on ethylamine.[1],[2] It is produced from crotonyl-CoA by crotonyl-CoA reductase/carboxylase and modified by ethylmalonyl-CoA mutase to make methylsuccinyl-CoA.
Reference
[1]. Good, N.M., Martinez-Gomez, N.C., Beck, D.A.C., et al. Ethylmalonyl coenzyme A mutase operates as a metabolic control point in Methylobacterium extorquens AM1 J. Bacteriol. 197(4), 727-735 (2015).
[2]. Anthony, C. How half a century of research was required to understand bacterial growth on C1 and C2 compounds; the story of the serine cycle and the ethylmalonyl-CoA pathway Sci. Prog. 94(Pt 2), 109-137 (2011).
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