Fosfomycin Trometamol (Synonyms: Fosfomycin Tromethamine) |
| رقم الكتالوجGC43698 |
فوسفوميسين (MK-0955) تروميثامين هو حاجز دموي في الدماغ يخترق مضاد حيوي واسع الطيف عن طريق تثبيط مرحلة مبكرة من تركيب جدار الخلية بشكل لا رجعة فيه.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 78964-85-9
Sample solution is provided at 25 µL, 10mM.
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Fosfomycin trometamol is a broad-spectrum antibiotic that is active against Gram-negative and Gram-positive bacteria with MIC90 values of 8, 32, 4, and 32 µg/mL for ESBL E. coli, carbapenemase-producing K. pneumoniae, P. mirabilis, and methicillin-resistant S. saprophyticus, respectively, in a broth microdilution assay. It is an inhibitor of uridine diphospho-N-acetyl-D-glucosamine enolpyruvyl transferase (MurA) that enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters. Formulations containing fosfomycin trometamol have been used in the treatment of urinary tract infections.
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