Fosfomycin Trometamol (Synonyms: Fosfomycin Tromethamine) |
| カタログ番号GC43698 |
ホスホマイシン (MK-0955) トロメタミンは、細胞壁合成の初期段階を不可逆的に阻害することにより、血液脳関門を透過する広域抗生物質です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 78964-85-9
Sample solution is provided at 25 µL, 10mM.
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Fosfomycin trometamol is a broad-spectrum antibiotic that is active against Gram-negative and Gram-positive bacteria with MIC90 values of 8, 32, 4, and 32 µg/mL for ESBL E. coli, carbapenemase-producing K. pneumoniae, P. mirabilis, and methicillin-resistant S. saprophyticus, respectively, in a broth microdilution assay. It is an inhibitor of uridine diphospho-N-acetyl-D-glucosamine enolpyruvyl transferase (MurA) that enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters. Formulations containing fosfomycin trometamol have been used in the treatment of urinary tract infections.
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