[Des-Arg9]-Bradykinin (Synonyms: (Des-Arg9)-BK, (Des-Arg9)-Kallidin, (Des-Arg9)-KD, RPPGFSPF-OH) |
رقم الكتالوجGC35015 |
[Des-Arg9] - براديكينين هو ناهض لمستقبلات براديكينين (B1) الذي يعرض انتقائية لمستقبلات B1 على مستقبلات B2
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 15958-92-6
Sample solution is provided at 25 µL, 10mM.
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].
References:
[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.
Average Rating: 5
(Based on Reviews and 10 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *