4'-Ethynyl-2'-deoxyadenosine |
| رقم الكتالوجGC35130 |
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) ، مثبط النسخ العكسي للنيوكليوزيد (RT) ، هو عامل مضاد للفيروسات القهقرية وهو فعال ضد متغيرات فيروس نقص المناعة البشرية المقاومة للأدوية ، مع EC50 من 98 نانومتر في MT- 4 خلايا لمضاد HIV-1 النشاط
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 306305-07-7
Sample solution is provided at 25 µL, 10mM.
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4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1]. EC50: 98 nM (MT-4 cells)[1].
[1]. Ohrui H, et al. 4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Curr Drug Targets Infect Disord. 2001 May;1(1):1-10.
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