4'-Ethynyl-2'-deoxyadenosine |
| Catalog No.GC35130 |
La 4'-etinil-2'-desoxiadenosina (4'-E-dA), un inhibidor de la transcriptasa inversa (RT) nucleÓsido, es un agente antirretroviral que es potente contra las variantes del VIH resistentes a los medicamentos, con un EC50 de 98 nM en MT- 4 células para la actividad anti-VIH-1.
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Cas No.: 306305-07-7
Sample solution is provided at 25 µL, 10mM.
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4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1]. EC50: 98 nM (MT-4 cells)[1].
[1]. Ohrui H, et al. 4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Curr Drug Targets Infect Disord. 2001 May;1(1):1-10.
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