4'-Ethynyl-2'-deoxyadenosine |
| Catalog No.GC35130 |
뉴클레오사이드 역전사효소(RT) 억제제인 4'-에티닐-2'-데옥시아데노신(4'-E-dA)은 항레트로바이러스제로서 MT에서 98 nM의 EC50으로 약물 내성 HIV 변이체에 대해 강력합니다. 항 HIV-1 활성을 위한 4개의 세포.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 306305-07-7
Sample solution is provided at 25 µL, 10mM.
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4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1]. EC50: 98 nM (MT-4 cells)[1].
[1]. Ohrui H, et al. 4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Curr Drug Targets Infect Disord. 2001 May;1(1):1-10.
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