ABT-046 |
رقم الكتالوجGC35221 |
ABT-046 عبارة عن مادة أسيل CoA قوية وانتقائية وفعالة عن طريق الفم: مثبط ثنائي أسيل جلسرين أسيل ترانسفيراز 1 (DGAT-1) مع IC50s لكل من 8 نانومتر ضد الإنسان والفأر DGAT-1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1031336-60-3
Sample solution is provided at 25 µL, 10mM.
ABT-046 is a potent, selective, and orally efficacious acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50= 8 nM)[1].
[1]. Yeh VS, et al. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of Acyl-CoA: Diacylglycerol acyltransferase 1. J Med Chem. 2012 Feb 23;55(4):1751-1757.
Average Rating: 5
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