ABT-046 |
| Catalog No.GC35221 |
ABT-046은 인간 및 마우스 DGAT-1에 대해 IC50이 모두 8nM인 강력하고 선택적이며 경구 활성인 아실 CoA:디아실글리세롤 아실트랜스퍼라제 1(DGAT-1) 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1031336-60-3
Sample solution is provided at 25 µL, 10mM.
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ABT-046 is a potent, selective, and orally efficacious acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50= 8 nM)[1].
[1]. Yeh VS, et al. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of Acyl-CoA: Diacylglycerol acyltransferase 1. J Med Chem. 2012 Feb 23;55(4):1751-1757.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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